硫酸镁钠钾口服液与复方聚乙二醇电解质散对患者肠道清洁的对比研究 [中文引用][英文引用]

 【摘要】目的 对比硫酸镁钠钾口服液与聚乙二醇电解质散在结肠镜检查中对肠道清洁的效果。方法：随机选取2022年1月1日至2023年1月1日亳州市人民医院住院需结肠镜检查的患者200例，按随机数字表法，分为观察组（硫酸镁钠钾口服液）和对照组（复方聚乙二醇电解质散），统计两组肠道准备成功率、全结肠及各部分肠段的波士顿肠道准备评分（BBPS）、患者满意度、患者愿意再次使用本药物的比例及安全性。结果：观察组与对照组在各结肠段BBPS评分：全结肠7.8±1.4 vs 7.4±1.3，右半结肠 2.6±0.5 vs 2.3±0.5，横结肠 2.7±0.5 vs 2.5±0.6，左半结肠 2.7±0.5 vs 2.3±0.6，差异均有统计学意义（P＜0.05）；观察组肠道准备≥6分的占98%，对照组占91%（P＜0.05）；观察组不良反应发生率低于对照组，观察组愿意再次选择此次肠道清洁剂患者高于对照组（P＜0.05）。结论：硫酸镁钠钾口服液在肠道准备效果中优于聚乙二醇电解质散，患者易于接受。

 【Abstract】  Objective  To compare the efficacy of oral solution of magnesium sodium potassium sulfate and polyethylene glycol electrolyte powder on intestinal cleansing during colonoscopy. Methods  A total of 200 patients in Bozhou People's Hospital requiring colonoscopy from January 1, 2022 to January 1, 2023 were selected. According to random number table method, all patients were randomly divided into observation group (oral solution of magnesium sodium potassium sulfate) and control group (polyethylene glycol electrolyte powder). The success rate of intestinal preparation, the Boston bowel preparation scale (BBPS) of the whole colon and all parts of the intestine, patient satisfaction, the proportion of patients willing to re-use this drug and the safety of the two groups were analyzed respectively. Results  The BBPS scores of the whole colon and each segment of colon in the observation group and the control group showed 7.8±1.4 vs. 7.4±1.3 in the whole colon, 2.6±0.5 vs. 2.3±0.5 in the right colon, 2.7±0.5 vs. 2.5±0.6 in the transverse colon, 2.7±0.5 vs. 2.3±0.6 in the left colon, with statistically significant differences (P＜0.05). 98% of the observation group and 91% of the control group had intestinal preparation score ≥6 (P＜0.05). The incidence of adverse reactions in the observation group was lower than that in the control group, and the patients in the observation group who were willing to choose the intestinal cleanser again were more than the control group (P＜0.05). Conclusion  The oral solution of magnesium sodium potassium sulfate is better than polyethylene glycol electrolyte powder in the effects of intestinal preparation, which is easy to be accepted by patients.