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良性胃溃疡出血患者内镜治疗术后再出血的危险因素分析 [中文引用][英文引用]

Analysis of risk factors for rebleeding in patients with benign gastric ulcer bleeding after endoscopic treatment

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作者：丁亚梅1 田野2 钱进 3 陈梅1 季鸿颖1

作者(英文)：

单位：江苏南通海安市人民医院内镜中心1 消化内科3 南京江苏省人民医院老年消化科2

单位(英文)：

关键词：胃溃疡消化内镜出血危险因素

关键词(英文)：

分类号：

出版年·卷·期（页码）：2023·1·第5期（322-325）

DOI: 10.3877/cma.j.issn.2095-2015.2023.05.010

-----摘要：-------------------------------------------------------------------------------------------

【摘要】目的探讨消化内镜治疗后的胃溃疡出血患者术后再出血的危险因素。方法回顾性收集2020年1月至2022年12月，海安市人民医院收治的胃溃疡出血患者218例，均在消化内镜下止血，根据患者术后是否再次出血，将患者分为再出血组(n=34)和对照组(n=184)，比较两组患者临床特征，分析内镜治疗后的胃溃疡出血患者术后再出血的危险因素。结果两组患者溃疡大小、溃疡深度、多个病灶和Forrest分级等方面存在统计学差异(P<0.05)。溃疡大小≥2cm、溃疡深度≥5mm、多个病灶、Forrest Ⅰ级是消化内镜治疗后的胃溃疡出血患者术后再出血的独立危险因素(P<0.05)。与对照组比较，再出血组患者出院时间显著延长[(11.48±4.34)d 比 (9.45±4.12)d, P=0.009]；输血率显著增高(82.35% 比28.26%, P=0.000)；院内死亡率显著增高(11.76% 比 0.54%, P=0.000)。结论溃疡大小≥2cm、溃疡深度≥5mm、多个病灶、Forrest Ⅰ级是消化内镜治疗后的胃溃疡出血患者术后再出血的独立危险因素，可导致患者预后不良。

-----英文摘要：---------------------------------------------------------------------------------------

[Abstract] Objective To explore the risk factors of rebleeding in patients with gastric ulcer with hemorrhage after endoscopic treatment. Methods From January 2020 to December 2022, 218 patients with gastric ulcer with hemorrhage admitted to the Hai'an People's Hospital were retrospectively collected, all of whom underwent hemostasis under digestive endoscopy. Based on whether the patients experienced rebleeding after operation or not, the patients were divided into rebleeding group (n=34) and control group (n=184). The clinical characteristics between the two groups were compared, and the risk factors for postoperative rebleeding in gastric ulcer with hemorrhage patients treated with digestive endoscopy were analyzed. Results There were statistically significant differences between the two groups in terms of ulcer size, ulcer depth, multiple lesions and Forrest grading (P<0.05). Ulcer size ≥ 2 cm, ulcer depth ≥ 5 mm, multiple lesions and Forrest grade Ⅰ were independent risk factors for postoperative rebleeding in patients with gastric ulcer bleeding after endoscopic treatment (P<0.05). Compared with the control group, the discharge time of patients in the rebleeding group was significantly prolonged [(11.48±4.34) d vs. (9.45±4.12) d, P=0.009]; the blood transfusion rate significantly increased (82.35% vs. 28.26%, P=0.000); the hospital mortality rate significantly increased (11.76% vs. 0.54%, P=0.000). Conclusion Ulcer size ≥ 2 cm, ulcer depth ≥ 5 mm, multiple lesions and Forrest grade Ⅰ are independent risk factors for postoperative rebleeding in patients with gastric ulcer with hemorrhage after endoscopic treatment, which can lead to poor prognosis.

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中文著录格式: 丁亚梅1 ,,田野2 ,,钱进,3,陈梅1 ,,季鸿颖1.良性胃溃疡出血患者内镜治疗术后再出血的危险因素分析.中华消化病与影像杂志(电子版).2023;1(5):322-325.

英文著录格式: .Analysis of risk factors for rebleeding in patients with benign gastric ulcer bleeding after endoscopic treatment.No Title Settings.2023;1(5):322-325.